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Phosphoproteomics Study Based on In Vivo Inhibition Reveals Sites of Calmodulin‐Dependent Protein Kinase II Regulation in the Heart

BACKGROUND: The multifunctional Ca(2+)‐ and calmodulin‐dependent protein kinase II (CaMKII) is a crucial mediator of cardiac physiology and pathology. Increased expression and activation of CaMKII has been linked to elevated risk for arrhythmic events and is a hallmark of human heart failure. A usef...

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Detalles Bibliográficos
Autores principales: Scholten, Arjen, Preisinger, Christian, Corradini, Eleonora, Bourgonje, Vincent J., Hennrich, Marco L., van Veen, Toon A. B., Swaminathan, Paari D., Joiner, Mei‐Ling, Vos, Marc A., Anderson, Mark E., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828808/
https://www.ncbi.nlm.nih.gov/pubmed/23926118
http://dx.doi.org/10.1161/JAHA.113.000318