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The actin filament cross-linker L-plastin confers resistance to TNF-α in MCF-7 breast cancer cells in a phosphorylation-dependent manner

We used a tumour necrosis factor (TNF)-α resistant breast adenocarcinoma MCF-7 cell line to investigate the involvement of the actin cytoskeleton in the mechanism of cell resistance to this cytokine. We found that TNF resistance correlates with the loss of cell epithelial properties and the gain of...

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Detalles Bibliográficos
Autores principales: Janji, Bassam, Vallar, Laurent, Tanoury, Ziad Al, Bernardin, François, Vetter, Guillaume, Schaffner-Reckinger, Elisabeth, Berchem, Guy, Friederich, Evelyne, Chouaib, Salem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828844/
https://www.ncbi.nlm.nih.gov/pubmed/19799649
http://dx.doi.org/10.1111/j.1582-4934.2009.00918.x