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Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells

Fibroblast growth factor receptor-1 (Fgfr1) gene knockout impairs cardiac and haematopoietic development in murine embryonic stem cells (mESC). In FGFR1, tyrosine residues Y653 and Y654 are responsible for its tyrosine kinase (TK) activity whereas phosphorylated Y463 and Y766 represent docking sites...

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Detalles Bibliográficos
Autores principales:	Ronca, Roberto, Gualandi, Laura, Crescini, Elisabetta, Calza, Stefano, Presta, Marco, Dell’Era, Patrizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828861/ https://www.ncbi.nlm.nih.gov/pubmed/19549074 http://dx.doi.org/10.1111/j.1582-4934.2009.00805.x

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