Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

An increasing number of epilepsy patients are afflicted with drug-resistant temporal lobe epilepsy (TLE) and require alternative therapeutic approaches. High-affinity glycine receptors (haGlyRs) are functionally adapted to tonic inhibition due to their response to hippocampal ambient glycine, and th...

Descripción completa

Detalles Bibliográficos
Autores principales: Eichler, Sabrina A, Kirischuk, Sergei, Jüttner, René, Schafermeier, Philipp K, Legendre, Pascal, Lehmann, Thomas-Nicolas, Gloveli, Tengis, Grantyn, Rosemarie, Meier, Jochen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828897/
https://www.ncbi.nlm.nih.gov/pubmed/19210758
http://dx.doi.org/10.1111/j.1582-4934.2008.00357.x

Ejemplares similares

Ejemplares similares