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Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms
Propolis has traditionally been used in curing infections and healing wounds and burns. Current researches have shown that propolis has antibacterial, antifungal and antiviral actions however, the pharmacological activity of propolis is highly variable depending on its geographic origin. There have...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828924/ https://www.ncbi.nlm.nih.gov/pubmed/24250366 |
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author | Jafarzadeh Kashi, Tahereh Sadat Kasra Kermanshahi, Ruha Erfan, Mohammad Vahid Dastjerdi, Elahe Rezaei, Yashar Tabatabaei, Fahimeh Sadat |
author_facet | Jafarzadeh Kashi, Tahereh Sadat Kasra Kermanshahi, Ruha Erfan, Mohammad Vahid Dastjerdi, Elahe Rezaei, Yashar Tabatabaei, Fahimeh Sadat |
author_sort | Jafarzadeh Kashi, Tahereh Sadat |
collection | PubMed |
description | Propolis has traditionally been used in curing infections and healing wounds and burns. Current researches have shown that propolis has antibacterial, antifungal and antiviral actions however, the pharmacological activity of propolis is highly variable depending on its geographic origin. There have been few studies on the effects of Iranian propolis on the oral microorganisms. In this in-vitro study, the antimicrobial activity of the ethanolic and water extracts of the Iranian propolis (10%, w/v) from north-east area of Tehran was evaluated. Susceptibility of the oral strains tested (Streptococcus mutans ATCC 35668; Streptococcus salivarius ATCC 9222; Staphylococcus aureus ATCC 25923; Enterococcus faecalis ATCC 9854 and Lactobacillus casei ATCC 39392) was evaluated using the agar diffusion method at a concentration of 20 mg/mL of propolis and the zones of growth inhibition were measured. Antibacterial activity was determined by using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at different concentrations of propolis. The ethanolic extract showed bacteriostatic and bactericidal activity against all the strains, with MIC and MBC ranges of 250-500 µg/mL. The MIC concentration of the water extract was 500 µg/mL against S. mutans and E. faecalis. The water extract showed bactericidal activity only against S. mutans (20 mg/mL). These results indicate that the ethanolic extract is probably more useful in the control of oral biofilms and subsequent dental caries development. However, to determine the consequence of the ethanolic extract of Iranian propolis on the oral mucosa, in-vivo studies of its possible effects are needed. |
format | Online Article Text |
id | pubmed-3828924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-38289242013-11-18 Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms Jafarzadeh Kashi, Tahereh Sadat Kasra Kermanshahi, Ruha Erfan, Mohammad Vahid Dastjerdi, Elahe Rezaei, Yashar Tabatabaei, Fahimeh Sadat Iran J Pharm Res Original Article Propolis has traditionally been used in curing infections and healing wounds and burns. Current researches have shown that propolis has antibacterial, antifungal and antiviral actions however, the pharmacological activity of propolis is highly variable depending on its geographic origin. There have been few studies on the effects of Iranian propolis on the oral microorganisms. In this in-vitro study, the antimicrobial activity of the ethanolic and water extracts of the Iranian propolis (10%, w/v) from north-east area of Tehran was evaluated. Susceptibility of the oral strains tested (Streptococcus mutans ATCC 35668; Streptococcus salivarius ATCC 9222; Staphylococcus aureus ATCC 25923; Enterococcus faecalis ATCC 9854 and Lactobacillus casei ATCC 39392) was evaluated using the agar diffusion method at a concentration of 20 mg/mL of propolis and the zones of growth inhibition were measured. Antibacterial activity was determined by using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at different concentrations of propolis. The ethanolic extract showed bacteriostatic and bactericidal activity against all the strains, with MIC and MBC ranges of 250-500 µg/mL. The MIC concentration of the water extract was 500 µg/mL against S. mutans and E. faecalis. The water extract showed bactericidal activity only against S. mutans (20 mg/mL). These results indicate that the ethanolic extract is probably more useful in the control of oral biofilms and subsequent dental caries development. However, to determine the consequence of the ethanolic extract of Iranian propolis on the oral mucosa, in-vivo studies of its possible effects are needed. Shaheed Beheshti University of Medical Sciences 2011 /pmc/articles/PMC3828924/ /pubmed/24250366 Text en © 2011 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jafarzadeh Kashi, Tahereh Sadat Kasra Kermanshahi, Ruha Erfan, Mohammad Vahid Dastjerdi, Elahe Rezaei, Yashar Tabatabaei, Fahimeh Sadat Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms |
title | Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms |
title_full | Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms |
title_fullStr | Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms |
title_full_unstemmed | Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms |
title_short | Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms |
title_sort | evaluating the in-vitro antibacterial effect of iranian propolis on oral microorganisms |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828924/ https://www.ncbi.nlm.nih.gov/pubmed/24250366 |
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