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Spheroid-forming subpopulation of breast cancer cells demonstrates vasculogenic mimicry via hsa-miR-299–5p regulated de novo expression of osteopontin

The growth of cancer cells as multicellular spheroids has frequently been reported to mimic the in vivo tumour architecture and physiology and has been utilized to study antitumour drugs. In order to determine the distinctive characteristics of the spheroid-derived cells compared to the correspondin...

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Detalles Bibliográficos
Autores principales: Shevde, Lalita A, Metge, Brandon J, Mitra, Aparna, Xi, Yaguang, Ju, Jingfang, King, Judy A, Samant, Rajeev S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829031/
https://www.ncbi.nlm.nih.gov/pubmed/19538464
http://dx.doi.org/10.1111/j.1582-4934.2009.00821.x