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Blockade of B-cell-activating factor suppresses lupus-like syndrome in autoimmune BXSB mice
B-cell-activating factor (BAFF), a member of the tumour necrosis factor superfamily, plays a critical role in the maturation, homeostasis and function of B cells. In this study, we demonstrated the biological outcome of BAFF blockade in BXSB murine lupus model, using a soluble fusion protein consist...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829033/ https://www.ncbi.nlm.nih.gov/pubmed/19627403 http://dx.doi.org/10.1111/j.1582-4934.2009.00817.x |