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Blockade of B-cell-activating factor suppresses lupus-like syndrome in autoimmune BXSB mice

B-cell-activating factor (BAFF), a member of the tumour necrosis factor superfamily, plays a critical role in the maturation, homeostasis and function of B cells. In this study, we demonstrated the biological outcome of BAFF blockade in BXSB murine lupus model, using a soluble fusion protein consist...

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Detalles Bibliográficos
Autores principales: Ding, Hanlu, Wang, Li, Wu, Xiongfei, Yan, Jun, He, Yani, Ni, Bing, Gao, Wenda, Zhong, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829033/
https://www.ncbi.nlm.nih.gov/pubmed/19627403
http://dx.doi.org/10.1111/j.1582-4934.2009.00817.x