Pathway analysis of genome-wide data improves warfarin dose prediction

BACKGROUND: Many genome-wide association studies focus on associating single loci with target phenotypes. However, in the setting of rare variation, accumulating sufficient samples to assess these associations can be difficult. Moreover, multiple variations in a gene or a set of genes within a pathw...

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Detalles Bibliográficos
Autores principales: Daneshjou, Roxana, Tatonetti, Nicholas P, Karczewski, Konrad J, Sagreiya, Hersh, Bourgeois, Stephane, Drozda, Katarzyna, Burmester, James K, Tsunoda, Tatsuhiko, Nakamura, Yusuke, Kubo, Michiaki, Tector, Matthew, Limdi, Nita A, Cavallari, Larisa H, Perera, Minoli, Johnson, Julie A, Klein, Teri E, Altman, Russ B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829086/
https://www.ncbi.nlm.nih.gov/pubmed/23819817
http://dx.doi.org/10.1186/1471-2164-14-S3-S11

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