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Nicotine Induces the Up-regulation of the α7-Nicotinic Receptor (α7-nAChR) in Human Squamous Cell Lung Cancer Cells via the Sp1/GATA Protein Pathway

Nicotine, the addictive component of cigarettes, promotes lung cancer proliferation via the α7-nicotinic acetylcholine receptor (α7-nAChR) subtype. The present manuscript explores the effect of nicotine exposure on α7-nAChR levels in squamous cell carcinoma of the lung (SCC-L) in vitro and in vivo....

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Detalles Bibliográficos
Autores principales:	Brown, Kathleen C., Perry, Haley E., Lau, Jamie K., Jones, Dennie V., Pulliam, Joseph F., Thornhill, Brent A., Crabtree, Clayton M., Luo, Haitao, Chen, Yi. Charlie, Dasgupta, Piyali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829154/ https://www.ncbi.nlm.nih.gov/pubmed/24089524 http://dx.doi.org/10.1074/jbc.M113.501601

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