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Improving Antigenic Peptide Vaccines for Cancer Immunotherapy Using a Dominant Tumor-specific T Cell Receptor

Vaccines that incorporate peptide mimics of tumor antigens, or mimotope vaccines, are commonly used in cancer immunotherapy and function by eliciting increased numbers of T cells that cross-react with the native tumor antigen. Unfortunately, they often elicit T cells that do not cross-react with or...

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Detalles Bibliográficos
Autores principales:	Buhrman, Jonathan D., Jordan, Kimberly R., Munson, Daniel J., Moore, Brandon L., Kappler, John W., Slansky, Jill E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829168/ https://www.ncbi.nlm.nih.gov/pubmed/24106273 http://dx.doi.org/10.1074/jbc.M113.509554

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