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Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review
Amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease, is a progressive and devastating disease involving both lower and upper motor neurons, typically following a relentless progression towards death. Therefore, all efforts must be made by the clinician to exclude altern...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829236/ https://www.ncbi.nlm.nih.gov/pubmed/24250855 |
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author | Ghasemi, Majid Fatehi, Farzad Asadi, Bahador Khorvash, Fariborz |
author_facet | Ghasemi, Majid Fatehi, Farzad Asadi, Bahador Khorvash, Fariborz |
author_sort | Ghasemi, Majid |
collection | PubMed |
description | Amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease, is a progressive and devastating disease involving both lower and upper motor neurons, typically following a relentless progression towards death. Therefore, all efforts must be made by the clinician to exclude alternative and more treatable entities. ALS with laboratory abnormalities of uncertain significance is a subgroup of ALS that occurs in association with laboratory defined abnormalities that are of uncertain significance to the pathogenesis of ALS. The clinical utility of these abnormalities and what they ultimately mean in patients with ALS is discussed here, along with a review of the literature. |
format | Online Article Text |
id | pubmed-3829236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-38292362013-11-18 Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review Ghasemi, Majid Fatehi, Farzad Asadi, Bahador Khorvash, Fariborz Iran J Neurol Review Paper Amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease, is a progressive and devastating disease involving both lower and upper motor neurons, typically following a relentless progression towards death. Therefore, all efforts must be made by the clinician to exclude alternative and more treatable entities. ALS with laboratory abnormalities of uncertain significance is a subgroup of ALS that occurs in association with laboratory defined abnormalities that are of uncertain significance to the pathogenesis of ALS. The clinical utility of these abnormalities and what they ultimately mean in patients with ALS is discussed here, along with a review of the literature. Tehran University of Medical Sciences 2012 /pmc/articles/PMC3829236/ /pubmed/24250855 Text en Copyright © 2012 Iranian Neurological Association, and Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Review Paper Ghasemi, Majid Fatehi, Farzad Asadi, Bahador Khorvash, Fariborz Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review |
title | Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review |
title_full | Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review |
title_fullStr | Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review |
title_full_unstemmed | Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review |
title_short | Amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: A brief review |
title_sort | amyotrophic lateral sclerosis with laboratory abnormalities of uncertain significance: a brief review |
topic | Review Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829236/ https://www.ncbi.nlm.nih.gov/pubmed/24250855 |
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