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Nuclear Factor-erythroid 2 (NF-E2) p45-related Factor-2 (Nrf2) Modulates Dendritic Cell Immune Function through Regulation of p38 MAPK-cAMP-responsive Element Binding Protein/Activating Transcription Factor 1 Signaling

Nrf2 is a redox-responsive transcription factor that has been implicated in the regulation of DC immune function. Loss of Nrf2 results in increased co-stimulatory molecule expression, enhanced T cell stimulatory capacity, and increased reactive oxygen species (ROS) levels in murine immature DCs (iDC...

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Detalles Bibliográficos
Autores principales:	Al-Huseini, Laith M. A., Aw Yeang, Han Xian, Sethu, Swaminathan, Alhumeed, Naif, Hamdam, Junnat M., Tingle, Yulia, Djouhri, Laiche, Kitteringham, Neil, Park, B. Kevin, Goldring, Christopher E., Sathish, Jean G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829319/ https://www.ncbi.nlm.nih.gov/pubmed/23775080 http://dx.doi.org/10.1074/jbc.M113.483420

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