Wingless-type family member 3A triggers neuronal polarization via cross-activation of the insulin-like growth factor-1 receptor pathway

Initial axonal elongation is essential for neuronal polarization and requires polarized activation of IGF-1 receptors (IGF-1r) and the phosphatidylinositol 3 kinase (PI3k) pathway. Wingless-type family growth factors (Wnts) have also been implied in the regulation of axonal development. It is not kn...

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Detalles Bibliográficos
Autores principales: Bernis, María E., Oksdath, Mariana, Dupraz, Sebastián, Nieto Guil, Alvaro, Fernández, Marisa M., Malchiodi, Emilio L., Rosso, Silvana B., Quiroga, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829478/
https://www.ncbi.nlm.nih.gov/pubmed/24298236
http://dx.doi.org/10.3389/fncel.2013.00194

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