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p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations

STUDY QUESTION: Is the environmental endocrine disruptor p,p′-dichlorodiphenyldichloroethylene (p,p′-DDE) able to induce non-genomic changes in human sperm and consequently affect functional sperm parameters? SUMMARY ANSWER: p,p′-DDE promoted Ca(2+) flux into human sperm by activating CatSper channe...

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Detalles Bibliográficos
Autores principales:	Tavares, Renata S., Mansell, Steven, Barratt, Christopher L.R., Wilson, Stuart M., Publicover, Stephen J., Ramalho-Santos, João
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829580/ https://www.ncbi.nlm.nih.gov/pubmed/24067601 http://dx.doi.org/10.1093/humrep/det372

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