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Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways

BACKGROUND: Plasmodium is the causal parasite of malaria, infectious disease responsible for the death of up to one million people each year. Glycerophospholipid and consequently membrane biosynthesis are essential for the survival of the parasite and are targeted by a new class of antimalarial drug...

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Detalles Bibliográficos
Autores principales: Sen, Partho, Vial, Henri J, Radulescu, Ovidiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829661/
https://www.ncbi.nlm.nih.gov/pubmed/24209716
http://dx.doi.org/10.1186/1752-0509-7-123