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α1-antitrypsin promotes SPLUNC1-mediated lung defense against Pseudomonas aeruginosa infection in mice

BACKGROUND: Pseudomonas aeruginosa (PA) infection is involved in various lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. However, treatment of PA infection is not very effective in part due to antibiotic resistance. α1-antitrypsin (A1AT) has been shown to reduce PA i...

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Detalles Bibliográficos
Autores principales:	Jiang, Di, Persinger, Rebecca, Wu, Qun, Gross, Ashley, Chu, Hong Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829673/ https://www.ncbi.nlm.nih.gov/pubmed/24209388 http://dx.doi.org/10.1186/1465-9921-14-122

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