The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells

Chemoresistance of cancer cells has been a severe problem in multiple types of cancers. One possibility is to combine different drugs with chemotherapy for improved efficacy. Cyclopamine blocks Hedgehog signaling by antagonizing Smo function, which induces tumor apoptosis. Here, we show that the com...

Descripción completa

Detalles Bibliográficos
Autores principales: Chai, Feng, Zhou, Jiangang, Chen, Cheng, Xie, Song, Chen, Xiao, Su, Ping, Shi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829677/
https://www.ncbi.nlm.nih.gov/pubmed/24250231
http://dx.doi.org/10.2147/OTT.S51914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829677/
https://www.ncbi.nlm.nih.gov/pubmed/24250231
http://dx.doi.org/10.2147/OTT.S51914

Ejemplares similares