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Enzymatic Cleavage of Type II Restriction Endonucleases on the 2′-O-Methyl Nucleotide and Phosphorothioate Substituted DNA

The effects of nucleotide analogue substitution on the cleavage efficiencies of type II restriction endonucleases have been investigated. Six restriction endonucleases (EcoRV, SpeI, XbaI, XhoI, PstI and SphI) were investigated respectively regarding their cleavage when substrates were substituted by...

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Detalles Bibliográficos
Autores principales:	Zhao, Guojie, Li, Jun, Tong, Zhaoxue, Zhao, Bin, Mu, Runqing, Guan, Yifu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829850/ https://www.ncbi.nlm.nih.gov/pubmed/24260216 http://dx.doi.org/10.1371/journal.pone.0079415

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