Cargando…
Cross-Activating Invariant NKT Cells and Kupffer Cells Suppress Cholestatic Liver Injury in a Mouse Model of Biliary Obstruction
Both Kupffer cells and invariant natural killer T (iNKT) cells suppress neutrophil-dependent liver injury in a mouse model of biliary obstruction. We hypothesize that these roles are interdependent and require iNKT cell-Kupffer cell cross-activation. Female, wild-type and iNKT cell-deficient C57Bl/6...
Autores principales: | Duwaerts, Caroline C., Sun, Eric P., Cheng, Chao-Wen, van Rooijen, Nico, Gregory, Stephen H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829879/ https://www.ncbi.nlm.nih.gov/pubmed/24260285 http://dx.doi.org/10.1371/journal.pone.0079702 |
Ejemplares similares
-
Leishmania donovani-induced expression of signal regulatory protein α on Kupffer cells enhances hepatic invariant NKT-cell activation
por: Beattie, Lynette, et al.
Publicado: (2010) -
Kupffer Cells Hasten Resolution of Liver Immunopathology in Mouse Models of Viral Hepatitis
por: Sitia, Giovanni, et al.
Publicado: (2011) -
CD169(+) MACROPHAGES PRESENT LIPID ANTIGENS TO MEDIATE EARLY ACTIVATION OF INVARIANT NKT CELLS IN LYMPH NODES
por: Barral, Patricia, et al.
Publicado: (2010) -
Mechanism of TGF-β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis
por: Qian, Jun, et al.
Publicado: (2020) -
Antitumor Immunity Produced by the Liver Kupffer Cells, NK Cells, NKT Cells, and CD8(+) CD122(+) T Cells
por: Seki, Shuhji, et al.
Publicado: (2011)