Polymorphisms in XPD Gene Could Predict Clinical Outcome of Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer Patients: A Meta-Analysis of 24 Studies

OBJECTIVE: Xeroderma pigmentosum group D (XPD) is an essential gene involved in the nucleotide excision repair (NER) pathway. Two commonly studied single nucleotide polymorphisms (SNPs) of XPD (Lys751Gln, A>C, rs13181; Asp312Asn, G>A, rs1799793) are implicated in the modulation of DNA repair c...

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Detalles Bibliográficos
Autores principales: Qin, Qin, Zhang, Chi, Yang, Xi, Zhu, Hongcheng, Yang, Baixia, Cai, Jing, Cheng, Hongyan, Ma, Jianxin, Lu, Jing, Zhan, Liangliang, Liu, Jia, Liu, Zheming, Xu, Liping, Sun, Xinchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829883/
https://www.ncbi.nlm.nih.gov/pubmed/24260311
http://dx.doi.org/10.1371/journal.pone.0079864

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