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A Novel Quantitative Kinase Assay Using Bacterial Surface Display and Flow Cytometry
The inhibition of tyrosine kinases is a successful approach for the treatment of cancers and the discovery of kinase inhibitor drugs is the focus of numerous academic and pharmaceutical laboratories. With this goal in mind, several strategies have been developed to measure kinase activity and to scr...
Autores principales: | Henriques, Sónia Troeira, Thorstholm, Louise, Huang, Yen-Hua, Getz, Jennifer A., Daugherty, Patrick S., Craik, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829888/ https://www.ncbi.nlm.nih.gov/pubmed/24260399 http://dx.doi.org/10.1371/journal.pone.0080474 |
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