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Neurosteroid 3α-Androstanediol Efficiently Counteracts Paclitaxel-Induced Peripheral Neuropathy and Painful Symptoms
Painful peripheral neuropathy belongs to major side-effects limiting cancer chemotherapy. Paclitaxel, widely used to treat several cancers, induces neurological symptoms including burning pain, allodynia, hyperalgesia and numbness. Therefore, identification of drugs that may effectively counteract p...
Autores principales: | Meyer, Laurence, Patte-Mensah, Christine, Taleb, Omar, Mensah-Nyagan, Ayikoe Guy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829913/ https://www.ncbi.nlm.nih.gov/pubmed/24260511 http://dx.doi.org/10.1371/journal.pone.0080915 |
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