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Hypoxia-Induced Reactive Oxygen Species Cause Chromosomal Abnormalities in Endothelial Cells in the Tumor Microenvironment
There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability. Here we investigated the role of hypoxia in th...
Autores principales: | Kondoh, Miyako, Ohga, Noritaka, Akiyama, Kosuke, Hida, Yasuhiro, Maishi, Nako, Towfik, Alam Mohammad, Inoue, Nobuo, Shindoh, Masanobu, Hida, Kyoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829944/ https://www.ncbi.nlm.nih.gov/pubmed/24260373 http://dx.doi.org/10.1371/journal.pone.0080349 |
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