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Mycophenolic Acid Inhibits Migration and Invasion of Gastric Cancer Cells via Multiple Molecular Pathways
Mycophenolic acid (MPA) is the metabolized product and active element of mycophenolate mofetil (MMF) that has been widely used for the prevention of acute graft rejection. MPA potently inhibits inosine monophosphate dehydrogenase (IMPDH) that is up-regulated in many tumors and MPA is known to inhibi...
Autores principales: | Dun, Boying, Sharma, Ashok, Teng, Yong, Liu, Haitao, Purohit, Sharad, Xu, Heng, Zeng, Lingwen, She, Jin-Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829969/ https://www.ncbi.nlm.nih.gov/pubmed/24260584 http://dx.doi.org/10.1371/journal.pone.0081702 |
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