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Relationship of serum thyroid stimulating hormone with body mass index in healthy adults

OBJECTIVE: To investigate any possible relationship between serum thyroid stimulating hormone (TSH) with body mass index (BMI) in healthy adults. MATERIALS AND METHODS: A total of 417 subjects aged 18-60 years who volunteered to get screened for thyroid illness with serum TSH have been enrolled from...

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Autores principales: Solanki, Amrita, Bansal, Shaifali, Jindal, Sushil, Saxena, Vivek, Shukla, Uma Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830292/
https://www.ncbi.nlm.nih.gov/pubmed/24251146
http://dx.doi.org/10.4103/2230-8210.119560
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author Solanki, Amrita
Bansal, Shaifali
Jindal, Sushil
Saxena, Vivek
Shukla, Uma Shankar
author_facet Solanki, Amrita
Bansal, Shaifali
Jindal, Sushil
Saxena, Vivek
Shukla, Uma Shankar
author_sort Solanki, Amrita
collection PubMed
description OBJECTIVE: To investigate any possible relationship between serum thyroid stimulating hormone (TSH) with body mass index (BMI) in healthy adults. MATERIALS AND METHODS: A total of 417 subjects aged 18-60 years who volunteered to get screened for thyroid illness with serum TSH have been enrolled from November 2012 to July 2013. Patients were divided into four groups based on BMI value: Underweight (BMI <18 kg/m(2)), normal (BMI: 18-22.9 kg/m(2)), overweight (BMI: 23-24.9 kg/m(2)), and obese (BMI ≥25 kg/m(2)). RESULT: In our study we found a significant variation (P < 0.001) in TSH with increasing BMI. As the BMI increased, mean TSH in the BMI range also increased. The individuals with higher BMI had higher TSH and this trend continued from underweight to Obese. The mean TSH of underweight group was 1.6036 mIU/L, normal weight group 2.1727 mIU/L, overweight group 2.2870 mIU/L and obese group 2.6416 mIU/L. CONCLUSION: In this study we found a significant relationship between serum TSH and BMI and mean TSH increased as BMI increased. Further large scale data from the population is required to confirm our findings.
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spelling pubmed-38302922013-11-18 Relationship of serum thyroid stimulating hormone with body mass index in healthy adults Solanki, Amrita Bansal, Shaifali Jindal, Sushil Saxena, Vivek Shukla, Uma Shankar Indian J Endocrinol Metab Brief Communication OBJECTIVE: To investigate any possible relationship between serum thyroid stimulating hormone (TSH) with body mass index (BMI) in healthy adults. MATERIALS AND METHODS: A total of 417 subjects aged 18-60 years who volunteered to get screened for thyroid illness with serum TSH have been enrolled from November 2012 to July 2013. Patients were divided into four groups based on BMI value: Underweight (BMI <18 kg/m(2)), normal (BMI: 18-22.9 kg/m(2)), overweight (BMI: 23-24.9 kg/m(2)), and obese (BMI ≥25 kg/m(2)). RESULT: In our study we found a significant variation (P < 0.001) in TSH with increasing BMI. As the BMI increased, mean TSH in the BMI range also increased. The individuals with higher BMI had higher TSH and this trend continued from underweight to Obese. The mean TSH of underweight group was 1.6036 mIU/L, normal weight group 2.1727 mIU/L, overweight group 2.2870 mIU/L and obese group 2.6416 mIU/L. CONCLUSION: In this study we found a significant relationship between serum TSH and BMI and mean TSH increased as BMI increased. Further large scale data from the population is required to confirm our findings. Medknow Publications & Media Pvt Ltd 2013-10 /pmc/articles/PMC3830292/ /pubmed/24251146 http://dx.doi.org/10.4103/2230-8210.119560 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Solanki, Amrita
Bansal, Shaifali
Jindal, Sushil
Saxena, Vivek
Shukla, Uma Shankar
Relationship of serum thyroid stimulating hormone with body mass index in healthy adults
title Relationship of serum thyroid stimulating hormone with body mass index in healthy adults
title_full Relationship of serum thyroid stimulating hormone with body mass index in healthy adults
title_fullStr Relationship of serum thyroid stimulating hormone with body mass index in healthy adults
title_full_unstemmed Relationship of serum thyroid stimulating hormone with body mass index in healthy adults
title_short Relationship of serum thyroid stimulating hormone with body mass index in healthy adults
title_sort relationship of serum thyroid stimulating hormone with body mass index in healthy adults
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830292/
https://www.ncbi.nlm.nih.gov/pubmed/24251146
http://dx.doi.org/10.4103/2230-8210.119560
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