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Failure of siblings to thrive beyond 5 years of age
We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830313/ https://www.ncbi.nlm.nih.gov/pubmed/24251167 http://dx.doi.org/10.4103/2230-8210.119580 |
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author | Jain, Himanshu Saxena, Vivek Jindal, Sushil Bansal, Shaifali |
author_facet | Jain, Himanshu Saxena, Vivek Jindal, Sushil Bansal, Shaifali |
author_sort | Jain, Himanshu |
collection | PubMed |
description | We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness. Polyglandular autoimmune syndrome Type-1 is a rare sporadic autosomal recessive disease. It is characterized by the existence of two or more endocrinal disorders. Patients may require lifelong hormone replacement therapy for survival. |
format | Online Article Text |
id | pubmed-3830313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38303132013-11-18 Failure of siblings to thrive beyond 5 years of age Jain, Himanshu Saxena, Vivek Jindal, Sushil Bansal, Shaifali Indian J Endocrinol Metab Brief Communication We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness. Polyglandular autoimmune syndrome Type-1 is a rare sporadic autosomal recessive disease. It is characterized by the existence of two or more endocrinal disorders. Patients may require lifelong hormone replacement therapy for survival. Medknow Publications & Media Pvt Ltd 2013-10 /pmc/articles/PMC3830313/ /pubmed/24251167 http://dx.doi.org/10.4103/2230-8210.119580 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communication Jain, Himanshu Saxena, Vivek Jindal, Sushil Bansal, Shaifali Failure of siblings to thrive beyond 5 years of age |
title | Failure of siblings to thrive beyond 5 years of age |
title_full | Failure of siblings to thrive beyond 5 years of age |
title_fullStr | Failure of siblings to thrive beyond 5 years of age |
title_full_unstemmed | Failure of siblings to thrive beyond 5 years of age |
title_short | Failure of siblings to thrive beyond 5 years of age |
title_sort | failure of siblings to thrive beyond 5 years of age |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830313/ https://www.ncbi.nlm.nih.gov/pubmed/24251167 http://dx.doi.org/10.4103/2230-8210.119580 |
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