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Failure of siblings to thrive beyond 5 years of age

We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness...

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Autores principales: Jain, Himanshu, Saxena, Vivek, Jindal, Sushil, Bansal, Shaifali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830313/
https://www.ncbi.nlm.nih.gov/pubmed/24251167
http://dx.doi.org/10.4103/2230-8210.119580
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author Jain, Himanshu
Saxena, Vivek
Jindal, Sushil
Bansal, Shaifali
author_facet Jain, Himanshu
Saxena, Vivek
Jindal, Sushil
Bansal, Shaifali
author_sort Jain, Himanshu
collection PubMed
description We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness. Polyglandular autoimmune syndrome Type-1 is a rare sporadic autosomal recessive disease. It is characterized by the existence of two or more endocrinal disorders. Patients may require lifelong hormone replacement therapy for survival.
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spelling pubmed-38303132013-11-18 Failure of siblings to thrive beyond 5 years of age Jain, Himanshu Saxena, Vivek Jindal, Sushil Bansal, Shaifali Indian J Endocrinol Metab Brief Communication We describe a family in which parents had consanguinity, being children of real sisters. They had given birth to five children. In their family, children remained healthy from birth to pre-school age and then started having symptoms around the age of 5 years and two of them succumbed to this illness. Polyglandular autoimmune syndrome Type-1 is a rare sporadic autosomal recessive disease. It is characterized by the existence of two or more endocrinal disorders. Patients may require lifelong hormone replacement therapy for survival. Medknow Publications & Media Pvt Ltd 2013-10 /pmc/articles/PMC3830313/ /pubmed/24251167 http://dx.doi.org/10.4103/2230-8210.119580 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Jain, Himanshu
Saxena, Vivek
Jindal, Sushil
Bansal, Shaifali
Failure of siblings to thrive beyond 5 years of age
title Failure of siblings to thrive beyond 5 years of age
title_full Failure of siblings to thrive beyond 5 years of age
title_fullStr Failure of siblings to thrive beyond 5 years of age
title_full_unstemmed Failure of siblings to thrive beyond 5 years of age
title_short Failure of siblings to thrive beyond 5 years of age
title_sort failure of siblings to thrive beyond 5 years of age
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830313/
https://www.ncbi.nlm.nih.gov/pubmed/24251167
http://dx.doi.org/10.4103/2230-8210.119580
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