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Endocrine management of male subfertility

Infertility in a couple is defined as failure to conceive after 12 months of regular unprotected intercourses. Male infertility due to impaired spermatogenesis may result from hypothalamic, pituitary or testicular disorders. Medical management of infertility associated with gonadotropin deficiencies...

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Detalles Bibliográficos
Autores principales: George, Belinda, Bantwal, Ganapathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830347/
https://www.ncbi.nlm.nih.gov/pubmed/24251201
http://dx.doi.org/10.4103/2230-8210.119500
Descripción
Sumario:Infertility in a couple is defined as failure to conceive after 12 months of regular unprotected intercourses. Male infertility due to impaired spermatogenesis may result from hypothalamic, pituitary or testicular disorders. Medical management of infertility associated with gonadotropin deficiencies have high success rate, but for primary testicular failure assisted reproduction techniques (ART) with adjunctive endocrine manipulation remains the best therapeutic option. This article discusses various therapeutic options and regimes using gonadotropins, anti-estrgens, aromatase inhibitors in management of male subfertiltiy.