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Angiotensin type 1a receptor-deficient mice develop diabetes-induced cardiac dysfunction, which is prevented by renin-angiotensin system inhibitors
BACKGROUND: Diabetes-induced organ damage is significantly associated with the activation of the renin-angiotensin system (RAS). Recently, several studies have demonstrated a change in the RAS from an extracellular to an intracellular system, in several cell types, in response to high ambient glucos...
Autores principales: | Yong, Qian Chen, Thomas, Candice M, Seqqat, Rachid, Chandel, Niketa, Baker, Kenneth M, Kumar, Rajesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830441/ https://www.ncbi.nlm.nih.gov/pubmed/24215514 http://dx.doi.org/10.1186/1475-2840-12-169 |
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