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Sickle cell trait is not associated with endemic Burkitt lymphoma: An ethnicity and malaria endemicity-matched case–control study suggests factors controlling EBV may serve as a predictive biomarker for this pediatric cancer
Endemic Burkitt lymphoma (eBL) is associated with Epstein–Barr virus (EBV) and Plasmodium falciparum coinfections. Malaria appears to dysregulate immunity that would otherwise control EBV, thereby contributing to eBL etiology. Juxtaposed to human genetic variants associated with protection from mala...
Autores principales: | Mulama, David H, Bailey, Jeffrey A, Foley, Joslyn, Chelimo, Kiprotich, Ouma, Collins, Jura, Walter GZO, Otieno, Juliana, Vulule, John, Moormann, Ann M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830732/ https://www.ncbi.nlm.nih.gov/pubmed/23832374 http://dx.doi.org/10.1002/ijc.28378 |
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