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Mutation of NPM1 and FLT3 Genes in Acute Myeloid Leukemia and Their Association with Clinical and Immunophenotypic Features

Background. Mutations in NPM1 and FLT3 genes represent the most frequent genetic alterations and important diagnostic and prognostic indicators in patients with acute myeloid leukemia (AML). Objective. We investigated the prevalence and clinical characteristics of NPM1 and FLT3 mutations in 161 pati...

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Detalles Bibliográficos
Autores principales: Chauhan, Pradeep Singh, Ihsan, Rakhshan, Singh, L. C., Gupta, Dipendra Kumar, Mittal, Vishakha, Kapur, Sujala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830788/
https://www.ncbi.nlm.nih.gov/pubmed/24288427
http://dx.doi.org/10.1155/2013/582569