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Virtual Screening and Biological Evaluation of Piperazine Derivatives as Human Acetylcholinesterase Inhibitors
The piperazine derivatives have been shown to inhibit human acetylcholinesterase. Virtual screening by molecular docking of piperazine derivatives 1-(1,4-benzodioxane-2-carbonyl) piperazine (K), 4-(4-methyl)-benzenesulfonyl-1-(1,4-benzodioxane-2-carbonyl) piperazine (S1), and 4-(4-chloro)-benzenesul...
Autores principales: | Varadaraju, Kavitha Raj, Kumar, Jajur Ramanna, Mallesha, Lingappa, Muruli, Archana, Mohana, Kikkeri Narasimha Shetty, Mukunda, Chethan Kumar, Sharanaiah, Umesha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830860/ https://www.ncbi.nlm.nih.gov/pubmed/24288651 http://dx.doi.org/10.1155/2013/653962 |
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