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Sodium and potassium competition in potassium-selective and non-selective channels

Potassium channels selectively conduct K(+), primarily to the exclusion of Na(+), despite the fact that both ions can bind within the selectivity filter. Here we perform crystallographic titration and single-channel electrophysiology to examine the competition of Na(+) and K(+) binding within the fi...

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Detalles Bibliográficos
Autores principales: Sauer, David B., Zeng, Weizhong, Canty, John, Lam, Yeeling, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831281/
https://www.ncbi.nlm.nih.gov/pubmed/24217363
http://dx.doi.org/10.1038/ncomms3721