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The NO/cGMP pathway inhibits transient cAMP signals through the activation of PDE2 in striatal neurons

The NO-cGMP signaling plays an important role in the regulation of striatal function although the mechanisms of action of cGMP specifically in medium spiny neurons (MSNs) remain unclear. Using genetically encoded fluorescent biosensors, including a novel Epac-based sensor (EPAC-S(H150)) with increas...

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Detalles Bibliográficos
Autores principales:	Polito, Marina, Klarenbeek, Jeffrey, Jalink, Kees, Paupardin-Tritsch, Danièle, Vincent, Pierre, Castro, Liliana R.V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831346/ https://www.ncbi.nlm.nih.gov/pubmed/24302895 http://dx.doi.org/10.3389/fncel.2013.00211

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