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The Contributions of HIF-Target Genes to Tumor Growth in RCC

Somatic mutations or loss of expression of tumor suppressor VHL happen in the vast majority of clear cell Renal Cell Carcinoma, and it’s causal for kidney cancer development. Without VHL, constitutively active transcription factor HIF is strongly oncogenic and is essential for tumor growth. However,...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Niu, Xiaohua, Liao, Lili, Cho, Eun-Ah, Yang, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832366/ https://www.ncbi.nlm.nih.gov/pubmed/24260413 http://dx.doi.org/10.1371/journal.pone.0080544

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