TERT Promoter Mutations Are Frequent in Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Activating mutations in the TERT promoter were recently identified in up to 71% of cutaneous melanoma. Subsequent studies found TERT promoter mutations in a wide array of other major human cancers. TERT promoter mutations lead to increased expression of telomerase, which maintains telomere length an...

Descripción completa

Detalles Bibliográficos
Autores principales: Griewank, Klaus G., Murali, Rajmohan, Schilling, Bastian, Schimming, Tobias, Möller, Inga, Moll, Iris, Schwamborn, Marion, Sucker, Antje, Zimmer, Lisa, Schadendorf, Dirk, Hillen, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832433/
https://www.ncbi.nlm.nih.gov/pubmed/24260374
http://dx.doi.org/10.1371/journal.pone.0080354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832433/
https://www.ncbi.nlm.nih.gov/pubmed/24260374
http://dx.doi.org/10.1371/journal.pone.0080354

Ejemplares similares