Gene-level Integrated Metric of negative Selection (GIMS) Prioritizes Candidate Genes for Nephrotic Syndrome

Nephrotic syndrome (NS) gene discovery efforts are now occurring in small kindreds and cohorts of sporadic cases. Power to identify causal variants in these groups beyond a statistical significance threshold is challenging due to small sample size and/or lack of family information. There is a need t...

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Detalles Bibliográficos
Autores principales: Sampson, Matthew G., Gillies, Christopher E., Ju, Wenjun, Kretzler, Matthias, Kang, Hyun Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832435/
https://www.ncbi.nlm.nih.gov/pubmed/24260533
http://dx.doi.org/10.1371/journal.pone.0081062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832435/
https://www.ncbi.nlm.nih.gov/pubmed/24260533
http://dx.doi.org/10.1371/journal.pone.0081062

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