Influence of the CXCL1 rs4074 A Allele on Alcohol Induced Cirrhosis and HCC in Patients of European Descent

BACKGROUND AND AIMS: CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Thus, CXCL1 might contribute to HSC activation and fibrogenesis. In the present study, we investigated the influence of the CXCL1 rs4074 polymorphism on the occurre...

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Detalles Bibliográficos
Autores principales: Nischalke, Hans Dieter, Berger, Cordula, Lutz, Philipp, Langhans, Bettina, Wolter, Franziska, Eisenhardt, Marianne, Krämer, Benjamin, Kokordelis, Pavlos, Glässner, Andreas, Müller, Tobias, Rosendahl, Jonas, Fischer, Janett, Berg, Thomas, Grünhage, Frank, Leifeld, Ludger, Soyka, Michael, Nattermann, Jacob, Sauerbruch, Tilman, Stickel, Felix, Spengler, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832473/
https://www.ncbi.nlm.nih.gov/pubmed/24260493
http://dx.doi.org/10.1371/journal.pone.0080848

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