Potentiation of the Effect of Thiazide Derivatives by Carbonic Anhydrase Inhibitors: Molecular Mechanisms and Potential Clinical Implications

BACKGROUND: Carbonic anhydrase inhibitors (CAI) are mild diuretics, hence not widely used in fluid overloaded states. They are however the treatment of choice for certain non-kidney conditions. Thiazides, specific inhibitors of Na-Cl cotransport (NCC), are mild agents and the most widely used diuret...

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Detalles Bibliográficos
Autores principales: Zahedi, Kamyar, Barone, Sharon, Xu, Jie, Soleimani, Manoocher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832474/
https://www.ncbi.nlm.nih.gov/pubmed/24260196
http://dx.doi.org/10.1371/journal.pone.0079327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832474/
https://www.ncbi.nlm.nih.gov/pubmed/24260196
http://dx.doi.org/10.1371/journal.pone.0079327

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