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Potentiation of the Effect of Thiazide Derivatives by Carbonic Anhydrase Inhibitors: Molecular Mechanisms and Potential Clinical Implications
BACKGROUND: Carbonic anhydrase inhibitors (CAI) are mild diuretics, hence not widely used in fluid overloaded states. They are however the treatment of choice for certain non-kidney conditions. Thiazides, specific inhibitors of Na-Cl cotransport (NCC), are mild agents and the most widely used diuret...
Autores principales: | Zahedi, Kamyar, Barone, Sharon, Xu, Jie, Soleimani, Manoocher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832474/ https://www.ncbi.nlm.nih.gov/pubmed/24260196 http://dx.doi.org/10.1371/journal.pone.0079327 |
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