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Discovery of Dihydrochalcone as Potential Lead for Alzheimer’s Disease: In Silico and In Vitro Study

By the virtual screening method we have screened out Dihydrochalcone as a top-lead for the Alzheimer’s disease using the database of about 32364 natural compounds. The binding affinity of this ligand to amyloid beta (A[Image: see text]) fibril has been thoroughly studied by computer simulation and e...

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Detalles Bibliográficos
Autores principales:	Viet, Man Hoang, Chen, Chun-Yu, Hu, Chin-Kun, Chen, Yun-Ru, Li, Mai Suan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832475/ https://www.ncbi.nlm.nih.gov/pubmed/24260164 http://dx.doi.org/10.1371/journal.pone.0079151

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