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Human Factor H-Related Protein 2 (CFHR2) Regulates Complement Activation

Mutations and deletions within the human CFHR gene cluster on chromosome 1 are associated with diseases, such as dense deposit disease, CFHR nephropathy or age-related macular degeneration. Resulting mutant CFHR proteins can affect complement regulation. Here we identify human CFHR2 as a novel alter...

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Detalles Bibliográficos
Autores principales:	Eberhardt, Hannes U., Buhlmann, Denise, Hortschansky, Peter, Chen, Qian, Böhm, Sascha, Kemper, Markus J., Wallich, Reinhard, Hartmann, Andrea, Hallström, Teresia, Zipfel, Peter F., Skerka, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832495/ https://www.ncbi.nlm.nih.gov/pubmed/24260121 http://dx.doi.org/10.1371/journal.pone.0078617

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