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High Glucose Attenuates Shear-Induced Changes in Endothelial Hydraulic Conductivity by Degrading the Glycocalyx

Diabetes mellitus is a risk factor for cardiovascular disease; however, the mechanisms through which diabetes impairs homeostasis of the vasculature have not been completely elucidated. The endothelium interacts with circulating blood through the surface glycocalyx layer, which serves as a mechanose...

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Detalles Bibliográficos
Autores principales: Lopez-Quintero, Sandra V., Cancel, Limary M., Pierides, Alexis, Antonetti, David, Spray, David C., Tarbell, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832508/
https://www.ncbi.nlm.nih.gov/pubmed/24260138
http://dx.doi.org/10.1371/journal.pone.0078954