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Comparison of Methods for Quantification of Global DNA Methylation in Human Cells and Tissues

DNA methylation is a key epigenetic modification which, in mammals, occurs mainly at CpG dinucleotides. Most of the CpG methylation in the genome is found in repetitive regions, rich in dormant transposons and endogenous retroviruses. Global DNA hypomethylation, which is a common feature of several...

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Detalles Bibliográficos
Autores principales: Lisanti, Sofia, Omar, Wan A. W., Tomaszewski, Bartłomiej, De Prins, Sofie, Jacobs, Griet, Koppen, Gudrun, Mathers, John C., Langie, Sabine A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832524/
https://www.ncbi.nlm.nih.gov/pubmed/24260150
http://dx.doi.org/10.1371/journal.pone.0079044