Regulatory Effects of Sestrin 3 (SESN3) in BCR-ABL Expressing Cells

Chronic myeloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL) are characterized by the presence of the BCR-ABL oncoprotein, which leads to activation of a plethora of pro-mitogenic and pro-survival pathways, including the mTOR signaling cascade. We provide evidence that in BCR-ABL expres...

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Detalles Bibliográficos
Autores principales: Vakana, Eliza, Arslan, Ahmet Dirim, Szilard, Amy, Altman, Jessica K., Platanias, Leonidas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832611/
https://www.ncbi.nlm.nih.gov/pubmed/24260131
http://dx.doi.org/10.1371/journal.pone.0078780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832611/
https://www.ncbi.nlm.nih.gov/pubmed/24260131
http://dx.doi.org/10.1371/journal.pone.0078780

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