IL-10 Inhibits the NF-κB and ERK/MAPK-Mediated Production of Pro-Inflammatory Mediators by Up-Regulation of SOCS-3 in Trypanosoma cruzi-Infected Cardiomyocytes

Trypanosoma cruzi (T. cruzi) infection produces an intense inflammatory response which is critical for the control of the evolution of Chagas’ disease. Interleukin (IL)-10 is one of the most important anti-inflammatory cytokines identified as modulator of the inflammatory reaction. This work shows t...

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Detalles Bibliográficos
Autores principales: Hovsepian, Eugenia, Penas, Federico, Siffo, Sofía, Mirkin, Gerardo A., Goren, Nora B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832617/
https://www.ncbi.nlm.nih.gov/pubmed/24260222
http://dx.doi.org/10.1371/journal.pone.0079445

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