Reduced Expression of the Vesicular Acetylcholine Transporter and Neurotransmitter Content Affects Synaptic Vesicle Distribution and Shape in Mouse Neuromuscular Junction

In vertebrates, nerve muscle communication is mediated by the release of the neurotransmitter acetylcholine packed inside synaptic vesicles by a specific vesicular acetylcholine transporter (VAChT). Here we used a mouse model (VAChT KD(HOM)) with 70% reduction in the expression of VAChT to investiga...

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Detalles Bibliográficos
Autores principales: Rodrigues, Hermann A., Fonseca, Matheus de C., Camargo, Wallace L., Lima, Patrícia M. A., Martinelli, Patrícia M., Naves, Lígia A., Prado, Vânia F., Prado, Marco A. M., Guatimosim, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832638/
https://www.ncbi.nlm.nih.gov/pubmed/24260111
http://dx.doi.org/10.1371/journal.pone.0078342

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