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Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer

Taxane based chemotherapy is the standard of care treatment in castration resistant prostate cancer (CRPC). There is convincing evidence that taxane therapy affects androgen receptor (AR) but the exact mechanisms have to be further elucidated. Our studies identified c-jun as a crucial key player whi...

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Detalles Bibliográficos
Autores principales: Tinzl, Martina, Chen, Binshen, Chen, Shao-Yong, Semenas, Julius, Abrahamsson, Per-Anders, Dizeyi, Nishtman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832643/
https://www.ncbi.nlm.nih.gov/pubmed/24260253
http://dx.doi.org/10.1371/journal.pone.0079573