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SUMOylation of PPARγ by Rosiglitazone Prevents LPS-Induced NCoR Degradation Mediating Down Regulation of Chemokines Expression in Renal Proximal Tubular Cells

Rosiglitazone (RGL), a synthetic agonist for peroxisome proliferator activated receptor γ (PPARγ), exhibits a potent anti-inflammatory activity by attenuating local infiltration of neutrophils and monocytes in the renal interstitium. To evaluate the mechanisms that account for inhibiting inflammator...

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Detalles Bibliográficos
Autores principales:	Lu, Ying, Zhou, Qiao, Shi, Yongbing, Liu, Jian, Zhong, Fang, Hao, Xu, Li, Cong, Chen, Nan, Wang, Weiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832667/ https://www.ncbi.nlm.nih.gov/pubmed/24260304 http://dx.doi.org/10.1371/journal.pone.0079815

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