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Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases

The peptide dendrimer provides novel strategies for various biological applications. Assembling of peptide in macromolecular structure is expected to give rational models as drugs, their delivery and diagnostic reagents. Improved understanding of virus structure and their molecular interactions with...

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Detalles Bibliográficos
Autores principales: Joshi, Vinay Ganeshrao, Dighe, Vikas D., Thakuria, Dimpal, Malik, Yashpal Singh, Kumar, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832690/
https://www.ncbi.nlm.nih.gov/pubmed/24426293
http://dx.doi.org/10.1007/s13337-013-0162-z
Descripción
Sumario:The peptide dendrimer provides novel strategies for various biological applications. Assembling of peptide in macromolecular structure is expected to give rational models as drugs, their delivery and diagnostic reagents. Improved understanding of virus structure and their molecular interactions with ligands have paved the way for treatment and control of emerging and re-emerging viral diseases. This review presents a brief account of a synthetic peptide dendrimer used for diagnostic, therapeutic and prophylactic applications. The designs comprise of multiple antigenic peptides which are being used as alternate synthetic antigens for different viruses.