HSP70/CD80 DNA vaccine inhibits airway remodeling by regulating the transcription factors T-bet and GATA-3 in a murine model of chronic asthma

INTRODUCTION: Airway remodeling is an important pathologic feature of chronic asthma. T-bet and GATA-3, the key transcription factors for differentiation toward Th1 and Th2 cells, play an important role in the pathogenesis of airway inflammation, airway hyperresponsiveness and airway remodeling. Pre...

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Detalles Bibliográficos
Autores principales: Yan, Li, Xiao-Ling, Shi, Zheng-Yan, Cheng, Guo-Ping, Li, Sen, Zhong, Zhuang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Experimental Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832816/
https://www.ncbi.nlm.nih.gov/pubmed/24273578
http://dx.doi.org/10.5114/aoms.2013.33180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832816/
https://www.ncbi.nlm.nih.gov/pubmed/24273578
http://dx.doi.org/10.5114/aoms.2013.33180

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